Tg(GFAP-CYP19A1)#Lire
Transgene Detail

Summary

• Symbol: Tg(GFAP-CYP19A1)#Lire
• Name: transgene insertion, Rena Li
• MGI ID: MGI:6472745
• Synonyms: hGFAP-Ar
• Transgene: Tg(GFAP-CYP19A1)#Lire Location: unknown Genetic Position: ChrUN, Syntenic
• Alliance: Tg(GFAP-CYP19A1)#Lire page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(GFAP-CYP19A1)#Lire expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CYP19A1 (1588)

  Cyp19a1

  (MGI:88587)

  human promoter, human gene

• Mutation details: The human glial fibrillary acidic protein gene promoter drives the expression of the human cytochrome P450 family 19 subfamily A member 1 gene in astrocytes. (J:296884)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:296884 Ma L, et al., Brain estrogen alters the effects of the antidepressant sertraline in middle-aged female and male mice. Mol Cell Endocrinol. 2020 Oct 1;516:110947
• All: 2 reference(s)