Tg(ACTA2-S1pr1)4Ytak
Transgene Detail

Summary

• Symbol: Tg(ACTA2-S1pr1)4Ytak
• Name: transgene insertion 4, Yoh Takuwa
• MGI ID: MGI:6471950
• Transgene: Tg(ACTA2-S1pr1)4Ytak Location: unknown
• Alliance: Tg(ACTA2-S1pr1)4Ytak page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTA2-S1pr1)4Ytak expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  S1pr1 (29733)

  S1pr1

  (MGI:1096355)

• The human promoter drives the rat cDNA. Line 4 was generated. (J:250320)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:250320 Ohkura SI, et al., Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6. PLoS One. 2017;12(8):e0182329
• All: 2 reference(s)