Dbn1^tm1.2Shira
Targeted Allele Detail

Summary

• Symbol: Dbn1^tm1.2Shira
• Name: drebrin 1; targeted mutation 1.2, Tomoaki Shirao
• MGI ID: MGI:6471940
• Synonyms: DAKO-Flox
• Gene: Dbn1 Location: Chr13:55621241-55635874 bp, - strand Genetic Position: Chr13, 30.06 cM
• Alliance: Dbn1^tm1.2Shira page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158208
• Parent Cell Line: MS12 (ES Cell)
• Strain of Origin: C57BL/6NSlc

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo cassette was inserted within exon 11a and exon 11a was floxed by homologous recombination. The neo cassette was removed. (J:158208)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dbn1 Mutation: 44 strains or lines available

References

• Original: J:158208 Kojima N, et al., Genetic disruption of the alternative splicing of drebrin gene impairs context-dependent fear learning in adulthood. Neuroscience. 2010 Jan 13;165(1):138-50
• All: 2 reference(s)