Mettl3^em1Wli
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mettl3^em1Wli
• Name: methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit; endonuclease-mediated mutation 1, Wei Li
• MGI ID: MGI:6471814
• Synonyms: Mettl3^flox
• Gene: Mettl3 Location: Chr14:52532298-52542585 bp, - strand Genetic Position: Chr14, 26.88 cM, cytoband C1
• Alliance: Mettl3^em1Wli page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR-targeting flanked exons 2-4 with loxP sites. (J:250433)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mettl3 Mutation: 45 strains or lines available

References

• Original: J:250433 Xu K, et al., Mettl3-mediated m(6)A regulates spermatogonial differentiation and meiosis initiation. Cell Res. 2017 Sep;27(9):1100-1114
• All: 6 reference(s)