Lpcat2b^MSN/GammMmmh
Spontaneous Allele Detail

Summary

• Symbol: Lpcat2b^MSN/GammMmmh
• Name: lysophosphatidylcholine acyltransferase 2B; MSN/GammMmmh
• MGI ID: MGI:6471793
• Synonyms: Lpcat2b^R112H
• Gene: Lpcat2b Location: Chr5:107579415-107582905 bp, + strand Genetic Position: Chr5, 52.23 cM, cytoband E5
• Alliance: Lpcat2b^MSN/GammMmmh page

Mutation origin

• Strain of Origin: MSN/GammMmmh

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This allele contains the following spontaneous mutation(s) that have a predicted consequential effect on the encoded peptide and that are specific to (fixed in) the MSN (Madison) strain used as a mania model, as compared to: the Hsd:ICR strain from which it is derived; the MaD2 (Maternal Defense 2) strain, which is also derived from Hsd:ICR but wasn't selected for mania; the C57BL/6J reference strain. Build GRCm38 genomic coordinates: g.chr5:107433141G>A (p.R112H). (J:267654)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lpcat2b Mutation: 16 strains or lines available

References

• Original: J:267654 Saul MC, et al., Genomic variants in an inbred mouse model predict mania-like behaviors. PLoS One. 2018;13(5):e0197624
• All: 1 reference(s)