Il36rn^tm1Maak
Targeted Allele Detail

Summary

• Symbol: Il36rn^tm1Maak
• Name: interleukin 36 receptor antagonist; targeted mutation 1, Masashi Akiyama
• MGI ID: MGI:6471771
• Synonyms: Il36rn^-
• Gene: Il36rn Location: Chr2:24166966-24172444 bp, + strand Genetic Position: Chr2, 16.31 cM
• Alliance: Il36rn^tm1Maak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296685
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A loxP flanked neomycin resistance cassette replaced part of exon 1 through the entire exon 3. (J:296685)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il36rn Mutation: 21 strains or lines available

Notes

HK3i ES (C57BL/6NJcl) cells were used to generated mice (J:296685).

References

• Original: J:296685 Shibata A, et al., Toll-like receptor 4 antagonist TAK-242 inhibits autoinflammatory symptoms in DITRA. J Autoimmun. 2017 Jun;80:28-38
• All: 5 reference(s)