Gjc1^tm2.3Kni
Targeted Allele Detail

Summary

• Symbol: Gjc1^tm2.3Kni
• Name: gap junction protein, gamma 1; targeted mutation 2.3, Kiyomasa Nishii
• MGI ID: MGI:6471727
• Gene: Gjc1 Location: Chr11:102690405-102710526 bp, - strand Genetic Position: Chr11, 66.48 cM
• Alliance: Gjc1^tm2.3Kni page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:231835
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change, Reporter)
• Mutation: Insertion
• Mutation details: The entire coding exon was flanked with loxP sites followed by an nls-LacZ. The original construct also included a floxed neo cassette. Cre-mediated recombination removed the selection cassette. (J:231835)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gjc1 Mutation: 35 strains or lines available

References

• Original: J:231835 Nishii K, et al., Connexin45 contributes to global cardiovascular development by establishing myocardial impulse propagation. Mech Dev. 2016 May;140:41-52
• All: 1 reference(s)