Khk^tm1Mial
Targeted Allele Detail

Summary

• Symbol: Khk^tm1Mial
• Name: ketohexokinase; targeted mutation 1, Miguel A Lanaspa
• MGI ID: MGI:6470928
• Synonyms: KHK^Fl
• Gene: Khk Location: Chr5:31078780-31088592 bp, + strand Genetic Position: Chr5, 16.9 cM
• Alliance: Khk^tm1Mial page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296576
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted into introns 2 and 4, creating a conditional-ready allele with exons 3 and 4 floxed. (J:296576)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Khk Mutation: 25 strains or lines available

References

• Original: J:296576 Andres-Hernando A, et al., Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction. Cell Metab. 2020 Jul 7;32(1):117-127.e3
• All: 2 reference(s)