Pcgf5^tm1.2Hko
Targeted Allele Detail

Summary

• Symbol: Pcgf5^tm1.2Hko
• Name: polycomb group ring finger 5; targeted mutation 1.2, Haruhiko Koseki
• MGI ID: MGI:6470904
• Gene: Pcgf5 Location: Chr19:36325729-36438370 bp, + strand Genetic Position: Chr19, 31.59 cM
• Alliance: Pcgf5^tm1.2Hko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:243420
• Parent Cell Line: M1/M-1 (ES Cell)
• Strain of Origin: (129 x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was floxed. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 2. (J:243420)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcgf5 Mutation: 19 strains or lines available

References

• Original: J:243420 Almeida M, et al., PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation. Science. 2017 Jun 09;356(6342):1081-1084
• All: 1 reference(s)