Pcgf3^tm1.2Hko
Targeted Allele Detail

Summary

• Symbol: Pcgf3^tm1.2Hko
• Name: polycomb group ring finger 3; targeted mutation 1.2, Haruhiko Koseki
• MGI ID: MGI:6470903
• Gene: Pcgf3 Location: Chr5:108609098-108654842 bp, + strand Genetic Position: Chr5, 53.13 cM
• Alliance: Pcgf3^tm1.2Hko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:243420
• Parent Cell Line: M1/M-1 (ES Cell)
• Strain of Origin: (129 x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 4 was floxed. Flp-mediated recombination removed the selection cassette inserted downstream of exon 4. Cre-mediated recombination removed exon 4. (J:243420)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcgf3 Mutation: 30 strains or lines available

References

• Original: J:243420 Almeida M, et al., PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation. Science. 2017 Jun 09;356(6342):1081-1084
• All: 2 reference(s)