Rr77^em1Tshir
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr77^em1Tshir
• Name: regulatory region 77; endonuclease-mediated mutation 1, Toshihiko Shiroishi
• MGI ID: MGI:6470872
• Synonyms: 9530036O11Rik^em1Tshir, delta7, delta SBE7, Rr(FC)^em1Tshir
• Gene: Rr77 Location: Chr5:29108175-29109698 bp Genetic Position: Chr5, Syntenic
• Alliance: Rr77^em1Tshir page

Mutation origin

• Strain of Origin: C57BL/6JJcl

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intergenic deletion
• Mutation details: CRISPR-targeting deleted 1524 bp of sequence that includes Shh brain enhancer 7 (SBE7). (J:282343)

Expression

In Mice Carrying this Mutation:

5 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr77 Mutation: 0 strains or lines available

References

• Original: J:282343 Sagai T, et al., SHH signaling mediated by a prechordal and brain enhancer controls forebrain organization. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23636-23642
• All: 1 reference(s)