Adad1^em2(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Adad1^em2(IMPC)J
• Name: adenosine deaminase domain containing 1; endonuclease-mediated mutation 2, Jackson
• MGI ID: MGI:6470849
• Synonyms: Adad1^em2
• Gene: Adad1 Location: Chr3:37117805-37165661 bp, + strand Genetic Position: Chr3, 18.3 cM, cytoband B
• Alliance: Adad1^em2(IMPC)J page
• IMPC: Adad1 gene page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 22 bp starting at chr3:37,064,309. (J:294176)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adad1 Mutation: 29 strains or lines available

References

• Original: J:294176 Snyder E, et al., ADAD1 and ADAD2, testis-specific adenosine deaminase domain-containing proteins, are required for male fertility. Sci Rep. 2020 Jul 14;10(1):11536
• All: 1 reference(s)