Ccdc88c^tm1Mat
Targeted Allele Detail

Summary

• Symbol: Ccdc88c^tm1Mat
• Name: coiled-coil domain containing 88C; targeted mutation 1, Masahide Takahashi
• MGI ID: MGI:6470667
• Synonyms: Daple^-
• Gene: Ccdc88c Location: Chr12:100877782-100995315 bp, - strand Genetic Position: Chr12, 51.11 cM
• Alliance: Ccdc88c^tm1Mat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254159
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The following elements were inserted into intron 2: a lox71 site, a splice acceptor site, a beta-geo beta-galactosidase reporter and neomycin resistance fusion gene, a loxP site, poly(A) signal sequence, a lox2272 site, pSP73 plasmid vector sequence and a lox511 site. (J:254159)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccdc88c Mutation: 122 strains or lines available

References

• Original: J:254159 Ishida-Takagishi M, et al., The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility. Nat Commun. 2012 May 29;3:859
• All: 1 reference(s)