Ptf1a^tm3.1Mgn
Targeted Allele Detail

Summary

• Symbol: Ptf1a^tm3.1Mgn
• Name: pancreas specific transcription factor, 1a; targeted mutation 3.1, Mark A Magnuson
• MGI ID: MGI:6470589
• Synonyms: Ptfl1a^tdTomatoMgn
• Gene: Ptf1a Location: Chr2:19450474-19452312 bp, + strand Genetic Position: Chr2, 13.37 cM, cytoband A2
• Alliance: Ptf1a^tm3.1Mgn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296396
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Epitope tag, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced by the tdTomato reporter gene, a Ptf1a coding sequence with an N-terminal epitope tagged Strep/Flag (NSF) fusion, and an FRT-flanked hygro cassette via RMCE using the loxed cassette acceptor (LCA) allele-containing ES cells. Flp-mediated recombination removed the selection cassette. (J:296396)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ptf1a Mutation: 29 strains or lines available

References

• Original: J:296396 Vanderbilt University, Labnodes. 2020
• All: 1 reference(s)