Map3k14^tm1Awai
Targeted Allele Detail

Summary

• Symbol: Map3k14^tm1Awai
• Name: mitogen-activated protein kinase kinase kinase 14; targeted mutation 1, Ari Waisman
• MGI ID: MGI:6467963
• Synonyms: Map3k14flox
• Gene: Map3k14 Location: Chr11:103110590-103158227 bp, - strand Genetic Position: Chr11, 66.8 cM
• Alliance: Map3k14^tm1Awai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260103
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 4. An F3-flanked puromycin resistance cassette with a 3' loxP site was inserted downstream of exon 6. (J:260103)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Map3k14 Mutation: 42 strains or lines available

References

• Original: J:260103 Mair F, et al., The NFkappaB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing gammadelta T cells. Elife. 2015 Dec 1;4:e10087
• All: 4 reference(s)