Spocd1^em2Doca
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spocd1^em2Doca
• Name: SPOC domain containing 1; endonuclease-mediated mutation 2, Donal O'Carroll
• MGI ID: MGI:6467408
• Synonyms: Spocd1^HA
• Gene: Spocd1 Location: Chr4:129823042-129850908 bp, + strand Genetic Position: Chr4, 63.43 cM
• Alliance: Spocd1^em2Doca page

Mutation origin

• Strain of Origin: (C57BL/6J x CBA/CaCrl)F1

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: A sequence encoding an HA epitope tag was inserted into the 3' end of the coding region of the gene to generate an endogenously expressed, fully functional protein tagged with HA at the C terminus. (J:295943)

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spocd1 Mutation: 30 strains or lines available

References

• Original: J:295943 Zoch A, et al., SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation. Nature. 2020 Aug;584(7822):635-639
• All: 3 reference(s)