Sfxn3^em1Btlr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sfxn3^em1Btlr
• Name: sideroflexin 3; endonuclease-mediated mutation 1, Bruce Beutler
• MGI ID: MGI:6466651
• Synonyms: Sfxn3-1i
• Gene: Sfxn3 Location: Chr19:45036015-45044822 bp, + strand Genetic Position: Chr19, 38.26 cM, cytoband D1
• Alliance: Sfxn3^em1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting of exon 3 inserted an A nucleotide. (J:289322)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sfxn3 Mutation: 19 strains or lines available

References

• Original: J:289322 Chen B, et al., Forward genetic analysis using OCT screening identifies Sfxn3 mutations leading to progressive outer retinal degeneration in mice. Proc Natl Acad Sci U S A. 2020 Jun 9;117(23):12931-12942
• All: 1 reference(s)