Sash1^tm1Akar
Targeted Allele Detail

Summary

• Symbol: Sash1^tm1Akar
• Name: SAM and SH3 domain containing 1; targeted mutation 1, Aly Karsan
• MGI ID: MGI:6466537
• Synonyms: Sash1^fl
• Gene: Sash1 Location: Chr10:8597983-8761814 bp, - strand Genetic Position: Chr10, 2.75 cM
• Alliance: Sash1^tm1Akar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:276950
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 3 and 4 are flanked by loxP sites, followed by a stop codon inserted at exon 5. (J:276950)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sash1 Mutation: 80 strains or lines available

References

• Original: J:276950 Coulombe P, et al., Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling. Cell Rep. 2019 May 7;27(6):1769-1780.e4
• All: 1 reference(s)