Plcb1^tm1Pgs
Targeted Allele Detail

Summary

• Symbol: Plcb1^tm1Pgs
• Name: phospholipase C, beta 1; targeted mutation 1, Pann-Ghill Suh
• MGI ID: MGI:6460327
• Synonyms: Plcb1^f, Plcb1^loxP
• Gene: Plcb1 Location: Chr2:134628084-135317178 bp, + strand Genetic Position: Chr2, 65.66 cM
• Alliance: Plcb1^tm1Pgs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:289428
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 11 was floxed. (J:289428)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plcb1 Mutation: 70 strains or lines available

References

• Original: J:289428 Hwang HJ, et al., Phospholipase C-beta1 potentiates glucose-stimulated insulin secretion. FASEB J. 2019 Oct;33(10):10668-10679
• All: 1 reference(s)