Adam28^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Adam28^em1Osb
• Name: a disintegrin and metallopeptidase domain 28; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6460278
• Gene: Adam28 Location: Chr14:68843476-68893291 bp, - strand Genetic Position: Chr14, 35.69 cM, cytoband D1
• Alliance: Adam28^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISRP-targeting of intron 2 through intron 22 deleted 47,616 bp. (J:290452)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adam28 Mutation: 56 strains or lines available

References

• Original: J:290452 Kiyozumi D, et al., NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility. Science. 2020 Jun 5;368(6495):1132-1135
• All: 1 reference(s)