Scx^tm1.1Skom
Targeted Allele Detail

Summary

• Symbol: Scx^tm1.1Skom
• Name: scleraxis scleraxis bHLH transcription factor; targeted mutation 1, Shingo Komura
• MGI ID: MGI:6459747
• Synonyms: Scx-EGFP, Scx^{tm1.1(EGFP)Skom}
• Gene: Scx Location: Chr15:76341652-76343658 bp, + strand Genetic Position: Chr15, 35.92 cM
• Alliance: Scx^tm1.1Skom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:293946
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES sequence and EGFP reporter gene were inserted downstream of the stop codon. Dre-recombination removed the rox-flanked selection cassette. (J:293946)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scx Mutation: 18 strains or lines available

References

• Original: J:293946 Komura S, et al., Induced pluripotent stem cell-derived tenocyte-like cells promote the regeneration of injured tendons in mice. Sci Rep. 2020 Mar 4;10(1):3992
• All: 3 reference(s)