Lncfao^em1Icm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lncfao^em1Icm
• Name: fatty acid oxidation promoting long noncoding RNA; endonuclease-mediated mutation 1, Ichiro Manabe
• MGI ID: MGI:6456687
• Synonyms: lncFAO KO1
• Gene: Lncfao Location: unknown Genetic Position: Chr13, Syntenic
• Alliance: Lncfao^em1Icm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Two sgRNAs were used with CRISPR/Cas9 technology to create knockout deletions. This allele is one of the two out of five deletion alleles that were selected and it has a 201 bp deletion that deletes most of exon 1. (J:294168)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lncfao Mutation: 0 strains or lines available

References

• Original: J:294168 Nakayama Y, et al., A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14365-14375
• All: 1 reference(s)