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Fhod1tm1.1Ryut
Targeted Allele Detail
Summary
Symbol: Fhod1tm1.1Ryut
Name: formin homology 2 domain containing 1; targeted mutation 1.1, Ryu Takeya
MGI ID: MGI:6455142
Gene: Fhod1  Location: Chr8:106055795-106074585 bp, - strand  Genetic Position: Chr8, 53.04 cM
Alliance: Fhod1tm1.1Ryut page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:293832
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe tareting vector replaced exon 1 with a lox71 site, lacZ reporter gene, FRT site, neomycin resistance cassette, FRT site, and loxP site. Flp-mediated recombination removed the selection cassette. (J:293832)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fhod1 Mutation:  57 strains or lines available
References
Original:  J:293832 Sanematsu F, et al., Fhod1, an actin-organizing formin family protein, is dispensable for cardiac development and function in mice. Cytoskeleton (Hoboken). 2019 Feb;76(2):219-229
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory