Prss55^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prss55^em1Osb
• Name: serine protease 55; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6454671
• Synonyms: Prss55^del
• Gene: Prss55 Location: Chr14:64312887-64327611 bp, - strand Genetic Position: Chr14, 33.35 cM
• Alliance: Prss55^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 6,527 bp encompassing the last 4 coding exons. (J:293896)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Prss55 Mutation: 18 strains or lines available

References

• Original: J:293896 Kobayashi K, et al., Prss55 but not Prss51 is required for male fertility in mice. Biol Reprod. 2020 Aug 4;103(2):223-234
• All: 1 reference(s)