Trip10^tm1.1Mskf
Targeted Allele Detail

Summary

• Symbol: Trip10^tm1.1Mskf
• Name: thyroid hormone receptor interactor 10; targeted mutation 1.1, Michael S Kapiloff
• MGI ID: MGI:6454003
• Synonyms: CIP4^f
• Gene: Trip10 Location: Chr17:57556455-57570665 bp, + strand Genetic Position: Chr17, 29.74 cM
• Alliance: Trip10^tm1.1Mskf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:293926
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting construct was designed to insert a loxP site upstream of exon 2 and an FRT-flanked neomycin cassette followed by a second loxP site downstream of exon 3. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:293926)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Trip10 Mutation: 30 strains or lines available

References

• Original: J:293926 Li X, et al., Calcineurin Abeta-Specific Anchoring Confers Isoform-Specific Compartmentation and Function in Pathological Cardiac Myocyte Hypertrophy. Circulation. 2020 Sep 8;142(10):948-962
• All: 1 reference(s)