Dach1^tm1Rgp
Targeted Allele Detail

Summary

• Symbol: Dach1^tm1Rgp
• Name: dachshund family transcription factor 1; targeted mutation 1, Richard G Pestell
• MGI ID: MGI:6453829
• Synonyms: Dach1^fl
• Gene: Dach1 Location: Chr14:98024289-98407201 bp, - strand Genetic Position: Chr14, 48.25 cM, cytoband E3
• Alliance: Dach1^tm1Rgp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221119
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 1 was flanked with a loxP site and a floxed neomycin resistance cassette. (J:221119)

Tumor Data

List all tumor models in MMHCdb carrying Dach1^tm1Rgp

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dach1 Mutation: 52 strains or lines available

References

• Original: J:221119 Chen K, et al., The Endogenous Cell-Fate Factor Dachshund Restrains Prostate Epithelial Cell Migration via Repression of Cytokine Secretion via a CXCL Signaling Module. Cancer Res. 2015 May 15;75(10):1992-2004
• All: 5 reference(s)