H2-K1^{d-em1(HLA-A*0201)Gpt}
Endonuclease-mediated Allele Detail

Summary

• Symbol: H2-K1^{d-em1(HLA-A*0201)Gpt}
• Name: histocompatibility 2, K1, K region; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:6452604
• Synonyms: H2-K^{emCin(HLA-A2.1)}
• Gene: H2-K1 Location: Chr17:34214986-34219316 bp, - strand Genetic Position: Chr17, 17.98 cM
• Alliance: H2-K1^{d-em1(HLA-A*0201)Gpt} page

Mutation origin

• Strain of Origin: NOD/ShiLtJGpt

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: CRISPR-targeting introduced a fragment of the genomic clone of the human HLA-A*0201 gene with humanized alpha1, alpha2, and alpha3 fused with murine transmembrane and intracellular regions. (J:293217)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any H2-K1 Mutation: 66 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 1 reference(s)