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Tg(Vil1-US28)L36Lira
Transgene Detail
Summary
Symbol: Tg(Vil1-US28)L36Lira
Name: transgene insertion L36, Sergio A Lira
MGI ID: MGI:6451679
Transgene: Tg(Vil1-US28)L36Lira  Location: unknown  
Alliance: Tg(Vil1-US28)L36Lira page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene places human cytomegalovirus (CMV VHL/E strain; human herpesvirus 5 (HHV-5)) gene US28 under control of the mouse villin 1 promoter. Three mouse lines were established; L18, L19 and L36. This line, L38, has intermediate expression in jejunum, ileum and colon epithelium: lower than L19, higher than L18. (J:166917)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:166917 Bongers G, et al., The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice. J Clin Invest. 2010 Nov 1;120(11):3969-78
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory