Lhfpl5^em1Phua
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lhfpl5^em1Phua
• Name: lipoma HMGIC fusion partner-like 5; endonuclease-mediated mutation 1, Pingbo Huang
• MGI ID: MGI:6450849
• Gene: Lhfpl5 Location: Chr17:28794330-28802567 bp, + strand Genetic Position: Chr17, 14.77 cM, cytoband B1
• Alliance: Lhfpl5^em1Phua page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated four stop codons in the first exon resulting in a knock-out allele. (J:292355)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lhfpl5 Mutation: 15 strains or lines available

References

• Original: J:292355 Li X, et al., Localization of TMC1 and LHFPL5 in auditory hair cells in neonatal and adult mice. FASEB J. 2019 Jun;33(6):6838-6851
• All: 1 reference(s)