Plac8^em1Hwl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Plac8^em1Hwl
• Name: placenta-specific 8; endonuclease-mediated mutation 1, Han-Woong Lee
• MGI ID: MGI:6449243
• Gene: Plac8 Location: Chr5:100701591-100720111 bp, - strand Genetic Position: Chr5, 48.49 cM, cytoband E3
• Alliance: Plac8^em1Hwl page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A 99 bp deletion mutation, abolishing the conventional translational start site, was generated by CRISPR/Cas9 genome editing technology. (J:278319)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plac8 Mutation: 14 strains or lines available

References

• Original: J:278319 Lee H, et al., CRISPR/Cas9-mediated generation of a Plac8 knockout mouse model. Lab Anim Res. 2018 Dec;34(4):279-287
• All: 1 reference(s)