Ptma^tm1Got
Targeted Allele Detail

Summary

• Symbol: Ptma^tm1Got
• Name: prothymosin alpha; targeted mutation 1, Otsuka GEN Research Institute
• MGI ID: MGI:6448366
• Gene: Ptma Location: Chr1:86454448-86458434 bp, + strand Genetic Position: Chr1, 43.96 cM, cytoband C5
• Alliance: Ptma^tm1Got page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:291693
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and a loxP-flanked MC1-neo cassette was inserted downstream of exon 3. (J:291693)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptma Mutation: 21 strains or lines available

References

• Original: J:291693 Halder SK, et al., Ggamma7-specific prothymosin alpha deletion causes stress- and age-dependent motor dysfunction and anxiety. Biochem Biophys Res Commun. 2020 Jan 29;522(1):264-269
• All: 1 reference(s)