Svs5^em1Natka
Endonuclease-mediated Allele Detail

Summary

• Symbol: Svs5^em1Natka
• Name: seminal vesicle secretory protein 5; endonuclease-mediated mutation 1, Natsuko Kawano
• MGI ID: MGI:6448101
• Gene: Svs5 Location: Chr2:164174685-164176314 bp, + strand Genetic Position: Chr2, 85.16 cM
• Alliance: Svs5^em1Natka page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/1)F1

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted downstream of the gene using gRNAs and an ssODN with CRISPR/Cas9 technology. (J:291572)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Svs5 Mutation: 7 strains or lines available

References

• Original: J:291572 Shindo M, et al., Deletion of a Seminal Gene Cluster Reinforces a Crucial Role of SVS2 in Male Fertility. Int J Mol Sci. 2019 Sep 14;20(18):4557
• All: 1 reference(s)