Npr2^tm4Fgr
Targeted Allele Detail

Summary

• Symbol: Npr2^tm4Fgr
• Name: natriuretic peptide receptor 2; targeted mutation 4, Fritz G Rathjen
• MGI ID: MGI:6446935
• Synonyms: Npr2^tm4(flox)Fgr
• Gene: Npr2 Location: Chr4:43631935-43651244 bp, + strand Genetic Position: Chr4, 23.05 cM
• Alliance: Npr2^tm4Fgr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263287
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Two loxP sites were inserted into the intronic sequences flanking exons 17 and 18 of the gene. (J:263287)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npr2 Mutation: 63 strains or lines available

References

• Original: J:263287 Troster P, et al., The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord. Front Mol Neurosci. 2018;11:19
• All: 2 reference(s)