Mr1^em3(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mr1^em3(IMPC)H
• Name: major histocompatibility complex, class I-related; endonuclease-mediated mutation 3, Harwell
• MGI ID: MGI:6441121
• Gene: Mr1 Location: Chr1:155003620-155022560 bp, - strand Genetic Position: Chr1, 66.45 cM, cytoband H1
• Alliance: Mr1^em3(IMPC)H page
• IMPC: Mr1 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele was generated at Medical Research Council Harwell using Cas9 and guides with spacer sequences AGTTGCAATACCAAAAGAAC, CACACCTACCAGAGAATGAT, GCAATACCAAAAGAACTGGC, and TTTGGTATTGCAACTCATGC that targeted exon(s) ENSMUSE00000159493.2. This resulted in deletion(s) of 4 bp (location: Chr1:155012387-155012390; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mr1 Mutation: 33 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)