Pycard^tm1Takam
Targeted Allele Detail

Summary

• Symbol: Pycard^tm1Takam
• Name: PYD and CARD domain containing; targeted mutation 1, Masafumi Takahashi
• MGI ID: MGI:6438118
• Synonyms: ASC^f
• Gene: Pycard Location: Chr7:127590545-127593039 bp, - strand Genetic Position: Chr7, 69.88 cM, cytoband F4
• Alliance: Pycard^tm1Takam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:289887
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Two loxP sites was inserted upstream of exon 1 and downstream of exon 3. (J:289887)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pycard Mutation: 16 strains or lines available

References

• Original: J:289887 Hishida E, et al., Crucial Role of NLRP3 Inflammasome in the Development of Peritoneal Dialysis-related Peritoneal Fibrosis. Sci Rep. 2019 Jul 17;9(1):10363
• All: 1 reference(s)