Rbm20^em3Hide
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rbm20^em3Hide
• Name: RNA binding motif protein 20; endonuclease-mediated mutation 3, Hidehito Kuroyanagi
• MGI ID: MGI:6437214
• Synonyms: delta26, Rbm20^KO
• Gene: Rbm20 Location: Chr19:53665737-53855511 bp, + strand Genetic Position: Chr19, 48.28 cM
• Alliance: Rbm20^em3Hide page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 26 nucleotide deletion (chr19:53843237..53843262) in exon 9 resulting in a null allele. (J:297234)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbm20 Mutation: 51 strains or lines available

References

• Original: J:297234 Ihara K, et al., A missense mutation in the RSRSP stretch of Rbm20 causes dilated cardiomyopathy and atrial fibrillation in mice. Sci Rep. 2020 Oct 27;10(1):17894
• All: 1 reference(s)