Cdkn1b^em2(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdkn1b^em2(IMPC)H
• Name: cyclin dependent kinase inhibitor 1B; endonuclease-mediated mutation 2, Harwell
• MGI ID: MGI:6437043
• Gene: Cdkn1b Location: Chr6:134897364-134902476 bp, + strand Genetic Position: Chr6, 65.77 cM
• Alliance: Cdkn1b^em2(IMPC)H page
• IMPC: Cdkn1b gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 Protein and 4 guide sequences CCGGGATATGGAAGAAGCGAGTC, AAGAAGCGAGTCAGCGCAAGTGG, TGAAGAACTAACCCGGGACTTGG, GGAGAAGCACTGCCGGGATATGG, which resulted in a Indel. (J:265051)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdkn1b Mutation: 26 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)