Gpr35^tm1.1Niess
Targeted Allele Detail

Summary

• Symbol: Gpr35^tm1.1Niess
• Name: G protein-coupled receptor 35; targeted mutation 1.1, Jan Hendrik Niess
• MGI ID: MGI:6436879
• Synonyms: Gpr35-IRES-tdTomato
• Gene: Gpr35 Location: Chr1:92878587-92914113 bp, + strand Genetic Position: Chr1, 46.65 cM, cytoband D
• Alliance: Gpr35^tm1.1Niess page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:300275
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES and tdTomato repoter gene were inserted downstream of the stop codon in exon 2. Flp-mediated recombination removed the selection cassette inserted upstream of exon 2. (J:300275)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr35 Mutation: 30 strains or lines available

References

• Original: J:300275 Kaya B, et al., Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1(+) Macrophages Regulates Intestinal Homeostasis. Cell Rep. 2020 Aug 4;32(5):107979
• All: 1 reference(s)