Tg(Kit-EGFP)3Poz
Transgene Detail

Summary

• Symbol: Tg(Kit-EGFP)3Poz
• Name: transgene insertion 3, Laura Pozzi
• MGI ID: MGI:6436272
• Transgene: Tg(Kit-EGFP)3Poz Location: unknown
• Alliance: Tg(Kit-EGFP)3Poz page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene construct consists of an enhanced GFP (EGFP) gene carrying at its 5' an HA epitope followed by a nuclear localization signal and, at its 3' end, stop codons, and a polyA addition site, was used as a reporter. The coding sequence of the EGFP gene was fused, at its initial ATG, to the first ATG of the first exon (and 6.7-kb 5 flanking sequence) of the Kit gene. Construct 3 used in this line also included a 4.5-kb XbaI-BamHI fragment of the first intron. (J:277552)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:277552 Cairns LA, et al., Kit regulatory elements required for expression in developing hematopoietic and germ cell lineages. Blood. 2003 Dec 1;102(12):3954-62
• All: 17 reference(s)