Mmab^tm1.2Mrl
Targeted Allele Detail

Summary

• Symbol: Mmab^tm1.2Mrl
• Name: methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human); targeted mutation 1.2, Merck Research Laboratory
• MGI ID: MGI:6436268
• Gene: Mmab Location: Chr5:114569095-114582121 bp, - strand Genetic Position: Chr5, 55.99 cM, cytoband F
• Alliance: Mmab^tm1.2Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 5 to 7 were flanked by loxP sites (size of loxP-flanked region: 1.5 kb). The conditional allele was generated after Flp-mediated recombination of the selection cassette. re-mediated recombination removed exons 5 to 7. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mmab Mutation: 20 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)