Pdcd1^tm1.1Mrl
Targeted Allele Detail

Summary

• Symbol: Pdcd1^tm1.1Mrl
• Name: programmed cell death 1; targeted mutation 1.1, Merck Research Laboratory
• MGI ID: MGI:6435725
• Gene: Pdcd1 Location: Chr1:93966027-93980278 bp, - strand Genetic Position: Chr1, 47.47 cM
• Alliance: Pdcd1^tm1.1Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 2 and 3 was flanked by loxP sites (size of loxP-flanked region: 1.5 kb).The positive selection marker (Puromycin resistance - PuroR) was flanked by FRT sites and inserted into intron 1. Flp-mediation removed the selection cassette. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdcd1 Mutation: 97 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 3 reference(s)