Ager^{tm1(H2B/Venus)Blh}
Targeted Allele Detail

Summary

• Symbol: Ager^{tm1(H2B/Venus)Blh}
• Name: advanced glycosylation end product-specific receptor; targeted mutation 1, Brigid L Hogan
• MGI ID: MGI:6435694
• Synonyms: Ager-H2b:Venus
• Gene: Ager Location: Chr17:34816836-34819910 bp, + strand Genetic Position: Chr17, 18.18 cM
• Alliance: Ager^{tm1(H2B/Venus)Blh} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A cassette encoding H2b:Venus fusion protein followed by poly and a FRT flanked neo cassette were recombined into the start codon of Ager gene by homologous recombination. (J:263983)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ager Mutation: 28 strains or lines available

References

• Original: J:263983 Chung MI, et al., Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation. Development. 2018 May 11;145(9):dev163014
• All: 2 reference(s)