Prkaa2^tm1.1Mrl
Targeted Allele Detail

Summary

• Symbol: Prkaa2^tm1.1Mrl
• Name: protein kinase, AMP-activated, alpha 2 catalytic subunit; targeted mutation 1.1, Merck Research Laboratory
• MGI ID: MGI:6435151
• Gene: Prkaa2 Location: Chr4:104887071-104967087 bp, - strand Genetic Position: Chr4, 49.05 cM
• Alliance: Prkaa2^tm1.1Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: The T172D point mutation was introduced into Prkaa2 exon 5. The positive selection marker (Puromycin resistance - PuroR) was flanked by F3 sites and introduced into intron 5. The constitutive point mutation allele was generated after Flp-mediated recombination. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkaa2 Mutation: 33 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)