Tg(RBP3-ELOVL4*)M69-53Mrl
Transgene Detail

Summary

• Symbol: Tg(RBP3-ELOVL4*)M69-53Mrl
• Name: transgene insertion M69-53, Merck Research Laboratory
• MGI ID: MGI:6434491
• Transgene: Tg(RBP3-ELOVL4*)M69-53Mrl Location: unknown
• Alliance: Tg(RBP3-ELOVL4*)M69-53Mrl page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(RBP3-ELOVL4*)M69-53Mrl expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ELOVL4 (6785)

  Elovl4

  (MGI:1933331)

  ELOVL4 cDNA harbors the AACTT deletion resulting in progressive photoreceptor degeneration

• Mutation details: A plasmid containing the human RBP3 promoter, a rabbit beta-globin intron and the human mutant ELOVL4 cDNA harboring the AACTT deletion resulting in progressive photoreceptor degeneration has been engineered. Line M69-53 has 2-3 transgenic copies integrated and shows intermediate expression level in ONL. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)