Lnpep^tm1.1Mrl
Targeted Allele Detail

Summary

• Symbol: Lnpep^tm1.1Mrl
• Name: leucyl/cystinyl aminopeptidase; targeted mutation 1.1, Merck Research Laboratory
• MGI ID: MGI:6434026
• Gene: Lnpep Location: Chr17:17747985-17846303 bp, - strand Genetic Position: Chr17, 9.77 cM
• Alliance: Lnpep^tm1.1Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: The H464Y and H468Y point mutations was introduced into exon 6 (TKIIAHELAHQWFGN to TKIIAYELAYQWFGN). A positive selection marker (puromycin resistance) was flanked by F3 sites and introduced into intron 6. The constitutive point mutation allele was generated after Flp-mediated recombination. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lnpep Mutation: 100 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)