Myo5a^d-x4R
Chemically induced Allele Detail

Summary

• Symbol: Myo5a^d-x4R
• Name: myosin VA; dilute intermediate 4 Oak Ridge
• MGI ID: MGI:6433851
• Synonyms: Myo5a^18ENURw
• Gene: Myo5a Location: Chr9:74978297-75130970 bp, + strand Genetic Position: Chr9, 42.26 cM
• Alliance: Myo5a^d-x4R page

Mutation origin

• Strain of Origin: (101/Rl x C3H/Rl)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU treatment caused a c.1222T>A mutation leading to a tyrosine to asparagine substitution at position 408 (p.Y408N). (J:47546)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myo5a Mutation: 266 strains or lines available

Notes

Dilute intermediate (d^x), when homozygous, causes a coat phenotype intermediate between wild-type and dilute (d) mice.

References

• Original: J:47546 Huang JD, et al., Molecular genetic dissection of mouse unconventional myosin-VA: head region mutations. Genetics. 1998 Apr;148(4):1951-61
• All: 1 reference(s)