Myo5a^d-x8R
Chemically induced Allele Detail

Summary

• Symbol: Myo5a^d-x8R
• Name: myosin VA; dilute intermediate 8 Oak Ridge
• MGI ID: MGI:6433847
• Synonyms: Myo5a^6PXENUe
• Gene: Myo5a Location: Chr9:74978297-75130970 bp, + strand Genetic Position: Chr9, 42.26 cM
• Alliance: Myo5a^d-x8R page

Mutation origin

• Strain of Origin: (101/Rl x C3H/Rl)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU and/or X-ray treatment caused a c.4556A>G mutation leading to an aspartic acid to glycine substitution at position 1519 (p.D1519G). (J:47547)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myo5a Mutation: 264 strains or lines available

Notes

Male parent received 300r X-rays five days prior to being injected with 100 mg/kg ENU. Dilute intermediate (d^x), when homozygous, causes a coat phenotype intermediate between wild-type and dilute (d) mice.

References

• Original: J:47547 Huang JD, et al., Molecular genetic dissection of mouse unconventional myosin-VA: tail region mutations. (Errata Genetics 1998 Nov;150:1331). Genetics. 1998 Apr;148(4):1963-72
• All: 1 reference(s)