Jak1^tm2.1Mrl
Targeted Allele Detail

Summary

• Symbol: Jak1^tm2.1Mrl
• Name: Janus kinase 1; targeted mutation 2.1, Merck Research Laboratory
• MGI ID: MGI:6433828
• Synonyms: Jak1^{tm1.1(K907A)Mrl}
• Gene: Jak1 Location: Chr4:101009564-101122479 bp, - strand Genetic Position: Chr4, 46.19 cM
• Alliance: Jak1^tm2.1Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: The K907A point mutation has been introduced into exon 20. The positive selection marker (Puromycin resistance - PuroR) has been flanked by FRT sites and inserted into intron 19. The constitutive PM allele has been generated after Flp-mediated recombination. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Jak1 Mutation: 51 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)