Gata4^tm1.1Hadj
Targeted Allele Detail

Summary

• Symbol: Gata4^tm1.1Hadj
• Name: GATA binding protein 4; targeted mutation 1.1, Anna-Katerina Hadjantonakis
• MGI ID: MGI:6433056
• Synonyms: Gata4^H2B-GFP
• Gene: Gata4 Location: Chr14:63436371-63509141 bp, - strand Genetic Position: Chr14, 33.24 cM
• Alliance: Gata4^tm1.1Hadj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:268273
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted between the 5' UTR and coding region a loxP site, a histone fused GFP (H2B-GFP) with a polyadenylation sequence, a loxP site, FRT-flanked neomycin resistance cassette and a triple FLAG epitope tag. Flp-mediated recombination removed the selection cassette. (J:268273)

Expression

In Mice Carrying this Mutation:

186 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata4 Mutation: 37 strains or lines available

References

• Original: J:268273 Simon CS, et al., A Gata4 nuclear GFP transcriptional reporter to study endoderm and cardiac development in the mouse. Biol Open. 2018 Dec 10;7(12):bio036517
• All: 1 reference(s)