Tg(CAG-CXCL8)1Yzhan
Transgene Detail

Summary

• Symbol: Tg(CAG-CXCL8)1Yzhan
• Name: transgene insertion 1, Yejia Zhang
• MGI ID: MGI:6432793
• Synonyms: pCALL-hIL8
• Transgene: Tg(CAG-CXCL8)1Yzhan Location: unknown
• Alliance: Tg(CAG-CXCL8)1Yzhan page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-CXCL8)1Yzhan expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  human	CXCL8 (3576)

• Tg(CAG-CXCL8)1Yzhan expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  chicken	CAG

• Mutation details: The transgenic construct contains a loxP-flanked lacZ-neomycin-polyA followed by a human CXCL8 (chemokine (C-X-C motif) ligand 8, also known as IL8) under the control of a CMV-enhanced chicken beta actin promoter (CAG). Founder line 1 has the highest CXCL8 (IL8) expression. (J:288179)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:288179 Brent JM, et al., Functional Deficits in Mice Expressing Human Interleukin 8. Comp Med. 2020 Apr 20
• All: 1 reference(s)